What is Hereditary Spastic Spinal Paralysis?
Hereditary spastic spinal paralysis (HSP), also known as spastic paraplegia or Strümpell-Lorrain’s disease, represents a group of disorders with damage to the long processes of the first MN (upper) in the cortex of the motor cortex. The common main symptom is “spastic paraparesis” (spastic paralysis of the legs). HSP is most likely genetic, but not all genetic alterations are yet known, so the location of the genetic alteration cannot always be revealed. The pure (uncomplicated) form essentially results in spasticity of the legs in young adulthood, there is then often a mutation in the SPG4 gene. In the complex (complicated) forms, on the other hand, there may be various additional symptoms such as coordination disorders, speech disorders, cognitive disorders or other symptoms.